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Late-Breaking Clinical Trials and Science

Wednesday, October 14, 2020

Main Arena

Late-Breaking Clinical Trial Session I, Co-sponsored by JACC: Vulnerable Plaque Detection and Treatment
11:00 AM – 12:00 PM
Moderator: Valentin Fuster, Renu Virmani
Discussants: Jagat Narula, Patrick O’Gara, Ron S. Waksman
11:00 AM
PROSPECT II: A Prospective Natural History Study Using NIRS-IVUS Imaging in Patients With Acute Myocardial Infarction
Lecturer: David Erlinge
11:20 AM
COMBINE (OCT–FFR): A Prospective Natural History Study Using OCT Imaging in Patients With Diabetes
Lecturer: Elvin Kedhi
11:40 AM
PROSPECT ABSORB: A Randomized Trial of Interventional Treatment of Vulnerable Plaques
Lecturer: Gregg Stone
Late-Breaking Clinical Science Session I, Co-sponsored by Circulation: Acute Myocardial Infarction Interventions
12:30 PM – 1:30 PM
Moderators:Roxana Mehran, Sunil V. Rao
Discussants: Dominick J. Angiolillo, Philippe Gabriel Steg, Marco Valgimigli
12:30 PM
NACMI: Outcomes From the North American COVID-19 STEMI Registry
Lecturer: Timothy Henry
12:45 PM
COMPARE CRUSH: A Randomized Trial of Prehospital Crushed vs Uncrushed Prasugrel in STEMI
Lecturer: Georgios Vlachojannis
1:00 PM
TICO-STEMI: A Randomized Trial of Ticagrelor Monotherapy vs Ticagrelor With Aspirin in STEMI
Lecturer: Byeong-Keuk Kim
1:15 PM
Bivalirudin vs Heparin in Patients With Myocardial Infarction: An Individual Patient Data Pooled Analysis
Lecturer: Gregg Stone

Thursday, October 15, 2020

Main Arena

Late-Breaking Clinical Trial Session II, Co-sponsored by JAMA: Valvular Heart Disease Therapies
11:00 AM – 12:00 PM
Moderators: Robert O. Bonow, Martin B. Leon
Discussants: Mayra Guerrero, Bernard Prendergast, Michael J. Reardon
11:00 AM
SCOPE II: A Randomized Trial of Two Self-expanding TAVR Bioprostheses
Lecturer: Corrado Tamburino
11:20 AM
REFLECT II: A Randomized Trial of a Cerebral Embolic Protection Device During TAVR
Lecturer: Jeffrey Moses
11:40 AM
MITHRAS: A Randomized Trial of ASD Closure After TMVR
Lecturer: Philipp Lurz
Late-Breaking Clinical Science Session II: Complex PCI Strategies
12:30 PM – 1:30 PM
Moderators: Ziad A. Ali, George D. Dangas
Discussants: Anthony H. Gershlick, Gary S. Mintz, Marco Valgimigli
12:30 PM
Disrupt CAD III: Safety and Effectiveness of Intravascular Lithotripsy for Treatment of Severe Coronary Calcification
Lecturer: Dean Kereiakes
12:45 PM
XIENCE 90/28: Assessment of Three-Month and One-Month DAPT After Everolimus-Eluting Stents in High-Bleeding Risk Patients
Lecturer: Roxana Mehran
1:00 PM
DEFINE-PCI: One-Year Outcomes in Patients With Post-PCI Residual Ischemia
Lecturer: Manesh Patel
1:15 PM
ULTIMATE: Three-Year Outcomes After IVUS-Guided vs Angiography Guided DES Implantation
Lecturer: Junjie Zhang

Friday, October 16, 2020

Main Arena

Late-Breaking Clinical Trial Session III, Co-sponsored by Lancet: Physiology-Guided Interventions
11:00 AM – 12:00 PM
Moderators: Stuart Spencer, Gregg W. Stone
Discussants: Bernard De Bruyne, William F. Fearon, Allen Jeremias, Rasha Al-Lamee
11:00 AM
FORECAST: A Randomized Trial of CTA/FFRCT Decision-making in Patients With Chest Pain
Lecturer: Nick Curzen
11:20 AM
TARGET FFR: A Randomized Trial of Physiology-Guided PCI Optimization
Lecturer: Damien Collison
11:40 AM
DEFINE-FLOW: An Observational Study of Deferred Lesions After FFR and CFR Assessment
Lecturer: Nils Johnson
Late-Breaking Clinical Science Session III: Aortic Stenosis and Mitral Regurgitation I
12:30 PM – 1:30 PM
Moderators: Samir R. Kapadia, Michael J. Mack
Discussants: Megan Coylewright, Gregg W. Stone, Vinod H. Thourani
12:30 PM
SOLVE-TAVI: One-Year Outcomes of a Factorial Randomized Trial of Self-expandable vs Balloon-expandable TAVR and General vs Local Anesthesia
Lecturer: Hans-Josef Feistritzer
12:45 PM
STS/ACC TVT Registry: Cerebral Embolic Protection and TAVR Outcomes
Lecturer: David J. Cohen
1:00 PM
MitraBridge: Outcomes of MitraClip Treatment as Bridge Therapy to Heart Transplantation
Lecturer: Cosmo Godino
1:15 PM
Global EXPAND: One-Year Outcomes With Third Generation MitraClip NTR and XTR Systems
Lecturer: Saibal Kar

Saturday, October 17, 2020

Main Arena

Late-Breaking Clinical Trial Session IV, Co-sponsored by European Heart Journal: Stent Trials and High-Bleeding Risk Patients
11:00 AM – 12:00 PM
Moderators: Filippo Crea, Marie-Claude Morice
Discussants: Donald Cutlip, Mamas Mamas, Pieter Smits, Ajay Kirtane
11:00 AM
Host-Reduce-Polytech-ACS: A Randomized Trial of Durable Polymer vs
Bioabsorbable Polymer DES in Patients With Acute Coronary Syndromes
Lecturer: Hyo-Soo Kim
11:20 AM
COBRA-REDUCE: A Randomized Trial of a Thromboresistant Polyzene F-Coated
Stent With 14 Days DAPT in High-Bleeding Risk Patients
Lecturer: Robert Byrne
11:40 AM
OPTIMIZE: A Randomized Trial of a Novel, Ultra Low Profile Fixed-Wire
Lecturer: Dean Kereiakes
Late-Breaking Clinical Science Session IV: Aortic Stenosis and Mitral Regurgitation II
12:30 PM – 1:30 PM
Moderators: Michael A. Borger, Howard C. Herrmann
Discussants: Vinayak N. Bapat, Jeroen J. Bax, David J. Cohen
12:30 PM
IREMMI: Outcomes of MitraClip in Patients With Acute Mitral
Regurgitation in AMI With and Without Cardiogenic Shock
Lecturer: Rodrigo Estevez-Loureiro
12:45 PM
SCOPE I: One-year Results From a Randomized Trial of Self-expanding vs
Balloon-expandable TAVR
Lecturer: Thomas Walther
1:00 PM
TRANSIT: Treatment of Failed TAVR With TAVR
Lecturer: Luca Testa
1:15 PM
PARTNER 2: Five-Year Follow-up From the Aortic Valve-in-Valve
Lecturer: Rebecca Hahn

Sunday, October 18, 2020

Main Arena

Endovascular 1: Late-Breaking Clinical Trials and Science
11:00 AM – 12:30 PM
Moderators: Sahil A. Parikh, Frank J. Veith
Discussants: Marc Bonaca, Robert A. Lookstein
11:00 AM
VOYAGER PAD: Long-term Safety of Drug-Coated Devices in Peripheral Artery Revascularization
Lecturer: Connie Hess
11:20 AM
IN.PACT BTK: A Randomzied Trial of Drug-Coated Balloon Angioplasty in the Infrapopliteal Arteries
Lecturer: Antonio Micari
11:35 AM
ILLUMENATE: Four-Year Results With a Low-Dose Paclitaxel Drug-Coated Balloon in De Novo And Restenotic Femoropopliteal Lesions
Lecturer: Andrew Holden
11:50 AM
TANGO: A Randomized Dose-Escalation Trial of Temsirolimus Adventitial Delivery to Improve Below the Knee Outcomes
Lecturer: Ehrin Armstrong
12:05 PM
FLASH Registry: Acute Hemodynamic Improvement With Percutaneous Mechanical Thrombectomy in a Real-world Pulmonary Embolism Population
Lecturer: Catalin Toma
12:18 PM
Anatomy of Human Accessory Renal Artery Peri-Arterial Renal Sympathetic Nerve for Renal Denervation
Lecturer: Yu Sato

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